Relationship between reproductive dysfunction and high cardiovascular risk

Krutova V.A., Dudnikova A.V.

Clinic, Kuban State Medical University, Ministry of Health of Russia, Krasnodar
The increased incidence of cardiovascular morbidity in women of childbearing age has become a trend in recent years, and therefore an interest has arisen in the female problem of cardiovascular morbidity and mortality. The aim of the study was to analyze the data available in the modern scientific literature on the possible pathophysiological mechanisms of an association between the main types of infertility and the risk of early cardiovascular events. The data of foreign and Russia papers on the research topic, which had been found in Pubmed and eLIBRARY and published in the last 7 years, were analyzed. According to current data, infertility is associated with cardiovascular disease. Understanding the pathogenetic mechanisms expands the possibilities for improving the mechanisms for providing comprehensive care to women with reproductive dysfunction.


cardiovascular risk
polycystic ovary syndrome


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Received 06.11.2018

Accepted 07.12.2018

About the Authors

Krutova, Victoria A., MD, professor of the Department of Obstetrics, Gynecology and Perinatology, chief physician of the Clinic Kuban State Medical University,
Ministry of Health of Russia; chief obstetrician-gynecologist of Southern Federal District of the Russian Federation.
350010, Russia, Krasnodar, Zipovskaya str. 4/1. Tel.: +78612570509. E-mail:
Dudnikova, Anna V., PhD, therapist of the highest qualification category of consultative-diagnostic department of the Clinic Kuban State Medical University,
Ministry of Health of Russia. 350010, Russia, Krasnodar, Zipovskaya str. 4/1. Tel.: +79186733223. E-mail:

For citations: Krutova V.A., Dudnikova A.V. Relationship between reproductive dysfunction and high cardiovascular risk. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2019; (5): 19-24. (in Russian)

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