Effects of anthropogenic chemicals on reproduction
Objective. To carry out a systematic analysis of the data available in the current literature on the effects of some anthropogenic chemicals on human fertility, including on the effectiveness of assisted reproductive technology programs.Syrkasheva A.G., Dolgushina N.V., Yarotskaya E.L.
Material and methods. The review includes the articles by foreign and Russian authors on this topic, which have been published in the Pubmed journals in the past 10 years.
Results. The authors analyze the literature data on the effects of heavy metals, phthalates, and bisphenol A on various aspects of human reproductive function. They present data on the possible pathogenetic mechanisms of action of anthropogenic chemicals on the quality of gametes and the efficiency of treatment for infertility.
Conclusion. It is necessary to further study the molecular mechanisms of negative action of toxicants on human fertility in order to determine management tactics in infertility patients.
Keywords
References
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Received 17.05.2017
Accepted 23.06.2017
About the Authors
Syrkasheva Anastasia Grigorievna, M.D., Ph.D., Researcher of the IVF Department, Research Center of Obstetrics, Gynecology and Perinatology,Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: a_syrkasheva@oparina4.ru
Dolgushina Nataliya Vitalievna, M.D., Ph.D., M.P.H., Head of R&D Department, Research Center of Obstetrics, Gynecology and Perinatology,
Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954384977. E-mail: n_dolgushina@oparina4.ru
Yarotskaya Ekaterina Lvovna, M.D., Ph.D., Head of the Department for International Cooperation, Research Center of Obstetrics, Gynecology and Perinatology,
Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954381166. E-mail: e_yarotskaya@oparina4.ru
For citations: Syrkasheva A.G., Dolgushina N.V., Yarotskaya E.L.
Effects of anthropogenic chemicals on reproduction.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (3): 16-21. (in Russian)
https://dx.doi.org/10.18565/aig.2018.3.16-21