Pregnancy management in women with malignant bone and soft tissue tumors (osteosarcoma and Ewing’s sarcoma)
Shmakov R.G., Akhmedova A.I., Kozyrko E.V.
Background. Currently, owing to therapy successes, it has often become possible to safely plan pregnancy and to give birth to babies in women with various cancers. Sarcomas occur mainly in adolescents and young people and are characterized by an aggressive clinical course. Pregnancy in patients with osteosarcoma and Ewing’s sarcoma is extremely rare and is associated with the higher risk of complications for both the mother and the fetus.
Description. In this connection, it is interesting to follow up pregnancies with osteosarcoma, Ewing’s sarcoma in 2 cases, and soft tissue sarcoma in 1 case.
Conclusion. Adequate initial therapy for the underlying disease, careful monitoring throughout pregnancy and its prolongation to fetal viability allowed these children born alive.
Keywords
pregnancy
osteosarcoma
Ewing’s sarcoma
malignant bone and soft tissue tumors
chemotherapy
antitumor treatment
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Received 16.04.2019
Accepted 19.04.2019
About the Authors
Roman G. Shmakov, MD, professor, Director of the Institute of Obstetrics, FSBI National Medical Research Center for Obstetrics, Gynecology and Perinatology namedafter Academician V.I.Kulakov. E-mail: r_shmakov@oparina4.ru
117997, Russia, Moscow, Oparina st., 4.
Aminat I. Akhmedova, postgraduate student, FSBI National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov. E-mail: akhmedovag@yandex.ru 117997, Russia, Moscow, Oparina st., 4.
Elena V. Kozyrko, Ph.D, researcher, FSBI National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov.
E-mail: lenochka525@gmail.com 117997, Russia, Moscow, Oparina st., 4
For citation: Shmakov R.G., Akhmedova A.I., Kozyrko E.V. Pregnancy management in women with malignant bone and soft tissue tumors (osteosarcoma and Ewing’s sarcoma).
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2019; 9:187-91. (InRussian)
https://dx.doi.org/10.18565/aig.2019.9.187-191
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