Tuberculosis and pregnancy
Background. Tuberculosis (TB) is difficult to diagnose in pregnant women; pregnancy management in patients with TB also poses certain challenges. The incidence of TB in pregnant women was 1.3 times higher than thatReikhrud T.A., Kulchavenya E.V., Myshkova E.P., Zhukova I.I., Zhukova E.M.
in the general population.
Description. The paper describes a case of recurrent multidrug-resistant pulmonary TB in a 24-year-old woman. The patient decided to maintain her current pregnancy, despite the use of anti-TB drugs and X-ray examination. The pregnancy was hard; the baby was born with birth defects.
The second case reflects a good maternal immunity because TB of the placenta was detected only after normal delivery and spontaneously cured TB of the uterine appendages was identified in three more months.
Conclusion. Pregnancy and TB are a negative concurrence for a woman; the patient should be oriented towards the prevention of an unplanned pregnancy.
Keywords
pregnancy
tuberculosis
pulmonary tuberculosis
extrapulmonary tuberculosis
urogenital tuberculosis
genital tuberculosis
infertility
placenta
tuberculosis of the placenta
Supplementary Materials
- Fig. 1. Disseminated pulmonary tuberculosis with signs of infiltration and destruction
- Fig. 2. Residual post-tuberculous changes: fibrosis in both lungs, a small number of high density zones
- Fig. 3. Caseous inflammation of placenta. Hematoxilin–eosin 100x
- Fig. 4. Mtb in tissue of placenta. Colored by Zheel-Nelsen
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Received 01.02.2017
Accepted 17.02.2017
About the Authors
Reykhrud Tatyana Anatolyevna, head of the therapeutic department, Novosibirsk Research Institute of Tuberculosis, Ministry of Health of Russia.630040, Russia, Novosibirsk, Okhotskaya str. 81A. Tel.: +73832037989. E-mail: urotub@yandex.ru
Kulchavena Ekaterina Valerievna, MD, chief researcher of Novosibirsk Research Institute of Tuberculosis, Ministry of Health of Russia, professor of the tuberculosis department at Novosibirsk State Medical University. 630040, Russia, Novosibirsk, Okhotskaya str. 81A. Tel.: +73832037989. E-mail: urotub@yandex.ru
Myshkova Elena Pavlovna, doctor of the Novosibirsk Research Institute of Tuberculosis, Ministry of Health of Russia.
630040, Russia, Novosibirsk, Okhotskaya str. 81A. Tel.: +73832037989. E-mail: urotub@yandex.ru
Zhukova Irina Ivanovna, head of the extrapulmonary department of the Novosibirsk Regional Tuberculosis Dispensary.
630075, Russia, Novosibirsk, Alexander Nevsky str. 9/1
Zhukova Elena Mikhailovna, MD, leading research assistant of the Novosibirsk Research Institute of Tuberculosis, Ministry of Health of Russia.
630040, Russia, Novosibirsk, Okhotskaya str. 81A. Tel.: +73832037989. E-mail: urotub@yandex.ru
For citations: Reikhrud T.A., Kulchavenya E.V., Myshkova E.P., Zhukova I.I., Zhukova E.M. Tuberculosis and pregnancyy. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (10): 124-9. (in Russian)
https://dx.doi.org/10.18565/aig.2017.10.124-129
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