Current methods for estimating the window of implantation in patients undergoing IVF treatment

Polovneva M.I., Korneeva I.E., Burmenskaya O.V.

National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia, Moscow
The paper provides a systems analysis of the data available in modern scientific literature on current methods for evaluating the markers of the window of implantation and on their search in patients with infertility. It describes the most significant markers of endometrial receptivity and methods for its assessment in infertile patients before embryo transfer in the in vitro fertilization (IVF) program. In consideration of highly contradictory data, further investigations are needed to search for predictors for the best day for implantation and to further understand the processes of synchronization between embryonic and endometrial development in order to enhance the effectiveness of an assisted reproductive technology program.

Keywords

window of implantation
endometrial receptivity biomarkers
in vitro fertilization
assisted reproductive technologies
repeated implantation failures

References

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Received 28.08.2017

Accepted 22.09.2017

About the Authors

Polovneva M.I., Postgraduate student at Department of Preservation and Restoration of the Reproductive Function, National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79854303833. E-mail: maria_mir18@mail.ru
Korneeva I.E., PhD, Leading Researcher at Department of Preservation and Restoration of the Reproductive Function, National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954382622. E-mail: i_korneeva@oparina4.ru
Bourmenskaya O.V., PhD, Senior Scientist at the Laboratory of Molecular Genetic Methods, National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954382292. E-mail: o_bourmenskaya@oparina4.ru

For citations: Polovneva M.I., Korneeva I.E., Burmenskaya O.V. Current methods for estimating the window of implantation in patients undergoing IVF treatment. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (7): 26-30. (in Russian)
https://dx.doi.org/10.18565/aig.2018.7.26-30

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