Modern pharmacotherapy for chronic recurrent cystitis: problems and opportunities

1. Foxman B. Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden. Infect. Dis. Clin. North Am. 2014; 28: 1. https://doi.org/10.1016/j.idc.2013.09.003.
2. Tandogdu Z., Wagenlehner F.M. Global epidemiology of urinary tract infections. Curr. Opin. Infect. Dis. 2016; 29(1): 73-9. https://doi.org/10.1097/QCO.0000000000000228.
3. Ikäheimo R., Siitonen A., Heiskanen T., Kärkkäinen U., Kuosmanen P., Lipponen P., Mäkelä P.H. Recurrence of urinary tract infection in a primary care setting: analysis of a 1-year follow-up of 179 women. Clin. Infect. Dis. 1996; 22: 91-9. https://doi.org/10.1093/clinids/22.1.91.
4. Geerlings S.E. Clinical presentations and epidemiology of urinary tract infections. Microbiol. Spectr. 2016; 4(5). https://doi.org/10.1128/microbiolspec.UTI-0002-2012.
5. Аляев Ю.Г., Глыбочко П.В., Пушкарь Д.Ю., ред. Россйскиие клинические рекомендации. Урология. М.: ГЭОТАР-Медиа; 2016. [Alyaev, Yu.G., Glybochko, PV, Pushkar, D.Yu., ed. Russian clinical guidelines. Urology. M .: GEOTAR-Media; 2016. (in Russian)]
6. Behzadi P., Behzadi E., Yazdanbod H., Aghapour R., Akbari Cheshmeh M., Salehian Omran D. A survey on urinary tract infections associated with the three most common uropathogenic bacteria. Maedica (Buchar.). 2010; 5(2): 111-5.
7. Colgan R., Williams M. Diagnosis and treatment of acute uncomplicated cystitis. Am. Fam. Physician. 2011; 84(7): 771-6.
8. Schito G.C., Naber K.G., Botto H., Palou J., Mazzei T., Gualco L., Marchese A. The ARESC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. Int. J. Antimicrob. Agents. 2009; 34(5): 407-13. https://doi.org/10.1016/j.ijantimicag.2009.04.012.
9. Paterson D.L. «Collateral damage» from cephalosporin or quinolone antibiotic therapy. Clin. Infect Dis. 2004; 38(4): 341-5. https://doi.org/10.1086/382690.
10. Hitzenbichler F., Simon M., Holzmann T., Iberer M., Zimmermann M., Salzberger B., Hanses F. Antibiotic resistance in E. coli isolates from patients with urinary tract infections presenting to the emergency department. Infection. 2018; 46(3): 325-31. https://doi.org/10.1007/s15010-018-1117-5.
11. Anger J., Lee U., Ackerman A.L., Chou R., Chughtai B., Clemens J.Q. et al. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J. Urol. 2019; 202(2): 282-9. https://doi.org/10.1097/JU.0000000000000296.
12. Knothe H., Schäfer V., Sammann A., Shah P.M. Influence of fosfomycin on the intestinal and pharyngeal flora of man. Infection. 1991; 19(1): 18-20.
13. Mavromanolakis E., Maraki S., Samonis G., Tselentis Y., Cranidis A. Effect of norfloxacin, trimethoprim-sulfamethoxazole and nitrofurantoin on fecal flora of women with recurrent urinary tract infections. J. Chemother. 1997; 9(3): 203-7. https://doi.org/10.1179/joc.1997.9.3.203.
14. Sullivan A., Edlund C., Nord C.E. Effect of antimicrobial agents on the ecological balance of human microflora. Lancet Infect. Dis. 2001; 1(2): 101-14. https://doi.org/10.1016/S1473-3099(01)00066-4.
15. Gupta K., Hooton T.M., Naber K.G., Wullt B., Colgan R., Miller L.G. et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitits and pyelonephritis in women: a 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin. Infect. Dis. 2011; 52(5): e103-20. https://doi.org/10.1093/cid/ciq257.
16. Рафальский В.В. Антибиотикорезистентность возбудителей неосложненных инфекций мочевых путей в Российской Федерации. Вестник урологии. 2018; 6(3): 50-6. https://doi.org/10.21886/2308-6424-2018-6-3-50-56.[Rafalsky V.V. Antibiotic resistance of pathogens of uncomplicated urinary tract infections in the Russian Federation. Herald of Urology. 2018; 6 (3): 50-6. https://doi.org/10.21886 / 2308-6424-2018-6-3-50-56(in Russian)]
17. Cai T., Nesi G., Mazzoli S., Meacci F., Lanzafame P., Caciagli P. et al. Asymptomatic bacteriuria treatment is associated with a higher prevalence of antibiotic resistant strains in women with urinary tract infections. Clin. Infect. Dis. 2015; 61(11): 1655-61. https://doi.org/10.1093/cid/civ696.
18. Brumfitt W., Smith G.W., Hamilton-Miller J.M., Gargan R.A. A clinical comparison between Macrodantin and trimethoprim for prophylaxis in women with recurrent urinary infections. J. Antimicrob. Chemother. 1985; 16(1): 111-20. https://doi.org/10.1093/jac/16.1.111.
19. Mozdzan M., Ruxer J., Siejka A., Loba J. The efficacy of chronic therapy of recurrent lower urinary tract infections with fosfomycin and nitrofurantoin in type 2 diabetic patients. Adv. Clin. Exp. Med. 2007; 16: 777.
20. Сlaussen K., Stocks E., Bhat D., Fish J., Rubin C.D. How common are pulmonary and hepatic adverse effects in older adults prescribed nitrofurantoin? J. Am. Geriatr. Soc. 2017; 65(6): 1316-20. https://doi.org/10.1111/jgs.14796.
21. By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel. American Geriatrics Society 2015 updated beers criteria for potentially inappropriate medication use in older adults. J. Am. Geriatr. Soc. 2015; 63(11): 2227-46. https://doi.org/10.1111/jgs.13702.
22. Ho J.M., Juurlink D.N. Considerations when prescribing trimethoprim-sulfamethoxazole. CMAJ. 2011; 183(16): 1851-8. https://doi.org/10.1503/cmaj.111152.
23. Costelloe C., Metcalfe C., Lovering A., Mant D., Hay A.D. Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis. BMJ. 2010; 340: 2096. https://doi.org/10.1136/bmj.c2096.
24. World Health Organization. Antimicrobial resistance. 2018. Available at: http://www.who.int/antimicrobial-resistance/en/
25. Kontiokari T., Sundqvist K., Nuutinen M., Pokka T., Koskela M., Uhari M. Randomised trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. BMJ. 2001; 322(7302): 1571. https://doi.org/10.1136/bmj.322.7302.1571.
26. Takahashi S., Hamasuna R., Yasuda M., Arakawa S., Tanaka K., Ishikawa K. et al. A randomized clinical trial to evaluate the preventive effect of cranberry juice (UR65) for patients with recurrent urinary tract infection. J. Infect. Chemother. 2013; 19(1): 112-7. https://doi.org/10.1007/s10156-012-0467-7.
27. Vostalova J., Vidlar A., Simanek V., Galandakova A., Kosina P., Vacek J. et al. Are high proanthocyanidins key to cranberry efficacy in the prevention of recurrent urinary tract infection? Phytother. Res. 2015; 29(10): 1559-67. https://doi.org/10.1002/ptr.5427.
28. Kranjcec B., Papes D., Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J. Urol. 2014; 32(1): 79-84. https://doi.org/10.1007/s00345-013-1091-6.
29. Porru D., Parmigiani A., Tinelli C., Barletta D., Choussos D., Di Franco C. et al. Oral D-mannose in recurrent urinary tract infections in women: A pilot study. J. Clin. Urol. 2014; 7: 208-13. https://doi.org/10.1177%2F2051415813518332
30. Зайцев А.В., Перепанова Т.С., Гвоздев М.Ю., Арефьева О.А. Инфекции мочевыводящих путей. Методические рекомендации № 57. Департамент здравоохранения города Москва; 2017; 26. [Zaitsev A.V., Perepanova T.S., Gvozdev M.J., Arefieva O.A. Urinary tract infections. Methodical recommendations number 57. The Moscow Department of Health. 2017; 26. (in Russian)]
31. Bauer H.W., Alloussi S., Egger G., Blümlein H.M., Cozma G., Schulman C.C. et al. A long-term, multicenter, double-blind study of an Escherichia coli extract (OM-89) in female patients with recurrent urinary tract infections. Eur. Urol. 2005; 47(4): 542-8. https://doi.org/10.1016/j.eururo.2004.12.009.
32. Naber K.G., Cho Y.H., Matsumoto T., Schaeffer A.S. Immunoactive prophylaxis of recurrent urinary tract infections: a meta-analysis. Int. J. Antimicrob. Agents. 2009; 33(2): 111-9. https://doi.org/10.1016/j.ijantimicag.2008.08.011.
33. Кульчавеня Е.В. Эффективность уро-ваксома при рецидивирующих инфекционно-воспалительных заболеваниях мочеполовой системы. Урология. 2011; 4: 7-11. [Kulchavenya E.V. The effectiveness of uro-vaksom with recurrent infectious and inflammatory diseases of the urogenital system. Urology. 2011; 4: 7–11. (in Russian)]

Received 10.06.2019

Accepted 21.06.2019