Polycystic ovary syndrome: Proteomic aspects
Objective. To analyze the data available in the literature on the proteomic markers of polycystic ovary syndrome (PCOS).Podzolkova N.M., Koloda Yu.A.
Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found in Pubmed on this topic.
Results. The paper describes on the proteomic markers reflecting the complex pathogenesis of PCOS and discusses their role in the diagnosis and treatment of this disease and the possibility of using in the prediction of in vitro fertilization outcomes.
Conclusion. It is necessary to conduct further investigations in the field of proteomics aimed at identifying new proteins and to validate the known biomarkers of PCOS in order to have an opportunity for their wide use in clinical practice.
Keywords
polycystic ovary syndrome
infertility
in vitro fertilization
proteomics
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Received 03.10.2016
Accepted 11.11.2016
About the Authors
Podzolkova N.M., MD, professor, head of the department of obstetrics and gynecology, Russian Medical Academy of Postgraduate Education.125993, Russia, Moscow, Barrikadnaya str. 2/1
Koloda Yu.A., associate professor, department of obstetrics and gynecology, Russian Medical Academy of Postgraduate Education.
125993, Russia, Moscow, Barrikadnaya str. 2/1. E-mail: julkol@yandex.ru
For citations: Podzolkova N.M., Koloda Yu.A. Polycystic ovary syndrome: Proteomic aspects. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (4): 53-60. (in Russian)
http://dx.doi.org/10.18565/aig.2017.4.53-60
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