Polymicrobial associations in the etiology of inflammatory diseases of the female genital organs
Objective. To assess the role of polymicrobial associations in the genesis of inflammatory diseases of the female genital organs and to determine the most rational approaches to diagnosis and treatment.Dikke G.B.
Material and methods. The materials of the World Health Organization, the Cochrane Society, the guidelines of leading professional societies, and clinical trials published on official websites and in open access were analyzed.
Results. There was information on the frequency of female genital tract inflammatory diseases caused by microbial combinations, as well as the established facts on resistance to antimicrobial agents, recommendations for their diagnosis and treatment, by indicating the strength of the evidence and convincingness of recommendations.
Conclusion. The recent changes in the epidemiology of inflammatory diseases, the prevalence of polymicrobial associations in their etiology, and the increasing microbial resistance require new approaches to the treatment and prevention of sexually transmitted infections and diseases accompanied by abnormal vaginal discharge.
Keywords
vaginitis
cervicitis
pelvic inflammatory diseases
polymicrobial infections
sexually transmitted infections
abnormal vaginal discharge
resistance
Supplementary Materials
- Table 1. The need for screening for the presence of infection associated with syndromal and approaches etiological diagnosis of diseases involving abnormal vaginal discharge
- Table 2. Comparative efficacy and features of metronidazole and clindamycin [43, 44]
- Table 3. Efficacy of combined formulations containing 500 mg metronidazole and miconazole 100 mg compared to a combined preparation containing 200 mg ternidazol [45]
- Figure. Dynamics of the sensitivity of various species of Candida: albicans * and non - albicans * * in Russia [6]
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Received 10.02.2017
Accepted 17.02.2017
About the Authors
Dikke Galina B., Honoured Science and Education, MD, professor of obstetrics, gynecology and reproductive medicine, faculty of continuing medical education,Peoples' Friendship University of Russia. 117198, Russia, Moscow, Miklukho-Maklaya str. 8. Tel.: +74954345300. E-mail: galadikke@yandex.ru
For citations: Dikke G.B. Polymicrobial associations in the etiology
of inflammatory diseases of the female genital organs.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (6): 151-8. (in Russian)
http://dx.doi.org/10.18565/aig.2017.6.151-8
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