Searching for optimal decisions and revising management tactics for patients with endometriosis

Chernukha G.E., Marchenko L.A., Gusev D.V.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow, Russia
Endometriosis is a common chronic disease that drastically reduces quality of life in women and requires long-term drug treatment due to the high risk of postoperative recurrences. The paper reviews the latest publications on pathogenesis and current management of women with endometriosis, by using noninvasive diagnostic methods and drug versus surgical treatment in order to avoid adverse outcomes of repeat surgical interventions.
Conclusion. Drug treatment with a good safety and tolerability profile should be the first-line therapy in patients with pelvic pain who are currently uninterested in pregnancy and have no indication for urgent surgical treatment. Progestins have many advantages over combined oral contraceptives for the treatment of endometriosis.

Keywords

endometriosis
surgical treatment
drug treatment
combined oral contraceptives
progestins
dienogest

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Received 31.07.2020

Accepted 05.08.2020

About the Authors

Galina E. Chernukha, MD, PhD, Professor, Head of the Department of Gynecological Endocrinology, FSBI «National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» Ministry of Healthcare of the Russian Federation. Tel.: +7(495)531–44–44. E-mail: g_chernukha@oparina4.ru.
117997, Russian Federation, Moscow, Ac. Oparin str., 4.
Larisa A. Marchenko, MD, PhD, Professor, Leading Research Officer of the Department of Gynecological Endocrinology, FSBI «National Medical Research Center
for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» Ministry of Healthcare of the Russian Federation.
Tel.: +7(495)531–44–44. E-mail: l_marchenko@yandex.ru.
117997, Russian Federation, Moscow, Ac. Oparin str., 4.
Dmitri V. Gusev, PhD, Research Officer of the Department of Gynecological Endocrinology, FSBI «National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» Ministry of Healthcare of the Russian Federation. E-mail: d_gusev@oparina4.ru.
117997, Russian Federation, Moscow, Ac. Oparin str., 4.

For citation: Chernukha G.E., Marchenko L.A., Gusev D.V. Searching for optimal decisions and revising management tactics for patients with endometriosis.
Akusherstvo i Ginekologiya/ Obstetrics and Gynecology. 2020; 8: 12-20 (in Russian).
https://dx.doi.org/10.18565/aig.2020.8.12-20

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