Main criteria and risk factors for the development of recurrent endometriosis
Objective: To analyze the data available in the current literature on the recurrence of different forms of endometriosis and to identify the main criteria and risk factors for the development of a relapse of the disease. The review article includes the data published by foreign and Russian authors in the Pubmed, UpToDate, and eLibrary databases on the keywords "endometriosis", "deep infiltrating endometriosis", and "recurrent endometriosis". Endometriosis is observed in 10% of reproductive-aged women and ranks third among gynecological diseases. The literature review focuses on risk factors for recurrent endometriosis. The term “recurrent endometriosis” is non-uniform and ambiguous; different studies describe various parameters of recurrent disease. This concept is used in different sources of literature in different ways: as recurrent pain, as the detection of new lesions by pelvic ultrasound or MRI, as a repeated increase in CA-125 levels, or as a surgical finding of new endometrioid implants during surgery unassociated with endometriosis.Senina D.N., Chuprynin V.D., Buralkina N.A., Chursin V.V., Smolnova T.Yu., Davidyan L.Yu., Abosov A.S.
Conclusion: At the moment, there are no unified clinical and molecular criteria for recurrent endometriosis. The lack of understanding of risk factors for recurrent endometriosis cannot build a unified strategy for early diagnosis, timely therapy and surgical treatment.
Keywords
endometriosis
common forms of endometriosis
deep infiltrating endometriosis
recurrent endometriosis
recurrent ovarian endometrioid cysts
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Received 26.07.2022
Accepted 11.10.2022
About the Authors
Daria N. Senina, PhD student, Surgical Department, I.M. Secenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University),119992, Russia, Moscow, Trubetskaya str., 2; Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology,
Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(904)189-30-63, seninadasha1995@gmail.com
Vladimir D. Chuprynin, PhD, Head of the Surgical Department, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(985)465-28-08, v_chuprynin@oparina4.ru
Natalya A. Buralkina, Dr. Med. Sci., Senior Researcher at Surgical Department, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(926)405-62-83, natalyaburalkina@yandex.ru
Vyacheslav V. Chursin, surgeon at the Department of General Surgery, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(926)971-21-03, v_chursin@oparina4.ru
Tatyana Yu. Smolnova, Dr. Med. Sci., Senior Reseacher at the Surgery Department, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(926)310-80-90, smoltat@list.ru
Liana Yu. Davidyan, Dr. Med. Sci., Professor of the Faculty of postgraduate medical and pharmaceutical education, Ulyanovsk State University,
432017, Russia, Ulyanovsk, Lva Tolstogo str., 42, +7(927)631-49-68, dliana2009@mail.ru
Аzizbek S. o’g’li Abosov, resident, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, abosovazizbek11@gmail.com
Authors’ contributions: Senina D.N. – information collection, literature data analysis, review formation, writing the text; Chuprynin V.D. – review formation, foreign literature analysis; Buralkina N.A. – review formation, foreign literature analysis, review article editing; Chursin V.V. – review formation, Russian literature analysis, review article editing; Smolnova T.Yu. – editing; Davidyan L.Yu. – review article editing; Abosov A.S. – assistance in preparing the article, as required.
Conflicts of interest: The authors declare that there are no conflicts of interest.
Funding: The source of funding is the state assignment "Comprehensive approach to diagnosing and choosing a surgical treatment option for reproductive-aged patients with deep infiltrating endometriosis".
For citation: Senina D.N., Chuprynin V.D., Buralkina N.A., Chursin V.V., Smolnova T.Yu., Davidyan L.Yu., Abosov A.S. Main criteria and risk factors for the development
of recurrent endometriosis.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2022; 10: 22-26 (in Russian)
https://dx.doi.org/10.18565/aig.2022.10.22-26
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