Experience of prolonged use of dienogest in the treatment of endometriosis
Background. Endometriosis is a chronic benign growth of endometrial-like tissues outside the uterine cavity. In the world, 6-10% of women of reproductive age are found, therefore, organ-preserving patience is the most preferred method of treatment. Progestins are the first-line drugs.Olina A.A. Meteleva T.A.
Description. This article presents two clinical observations of patients with adenomyosis, long-term (over 6 years) use dienoguest (visanne) at a dose of 2 mg per day. Against the background of the drug, there is a marked improvement in health, a decrease in the level of pain syndrome, a decrease in the size of the uterus according to ultrasound.
Conclusion. The presented clinical observations allow to recommend long-term therapy of adenomyosis with dienogest 2 mg (visanna drug), and confirm the high level of efficacy and safety of long-term therapy.
Keywords
endometriosis
adenomyosis
progestin
dienogest
References
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Received 08.06.2018
Accepted 22.06.2018
About the Authors
Anna A. Olina, MD, Deputy Director for Development, D.O. Ott Scientific Research Institute of Obstetrics, Gynecology and Reproduction.Russia, St. Petersburg, Mendeleevskaya line, 3. E-mail: olina29@mail.ru
Tatyana A. Meteleva, Assistant of the Department of Obstetrics and Gynecology, Academician E.A. Wagner Perm State Medical University, Ministry of Health of Russia. 614000, Russia, Perm, ul. Petropavlovskaya, 26
For citations: Olina A.A. Meteleva T.A. Experience of prolonged use of dienogest in the treatment of endometriosis. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (7): 97-102. (in Russian)
https://dx.doi.org/10.18565/aig.2018.7.97-102
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