Evaluation of the impact of intimate hygiene with Epigen Intim gel on discomfort in the area of external genital organs: results of an observational study

Tapilskaya N.I., Dolgushina V.F., Mingalyova N.V.

1) D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology, Russian Academy of Sciences, Saint Petersburg, Russia; 2) Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia, Saint Petersburg, Russia; 3) South Ural State Medical University; Ministry of Health of Russia, Chelyabinsk, Russia; 4) Faculty of Medicine, Kuban State Medical University, Krasnodar, Russia
Objective. To evaluate the impact of daily use of the intimate hygiene agent Epigen Intim on the cleanliness of vaginal smears, vaginal pH values, the frequency, duration, and intensity of discomfort in the area of external genital organs, as well as tolerance and satisfaction of the study participants with the use of the gel.
Materials and methods. The investigation included 741 women aged 14 to 69 years; their mean age was 37.69±0.47 years. The female participants were followed up for 90±7 days. They underwent vaginal pH metry, microscopic examination of urogenital discharge, a questionnaire survey containing questions about a patient’s complaints and lifestyle, and the features of using the test gel. The intensity of the discomfort experienced was estimated using the Wong-Baker scale.
Results. The daily use of the gel resulted in a decrease in the proportion of the study participants with pathological vaginal discharge from 30.86 to 5.43%, a decline in both that of participants with a pH value of over 4.5 from 81.18 to 50.88%. Discomfort assessment using the Wong-Baker scale showed that the mean score of discomfort intensity in the genital area decreased from 4.79 to 1.72. The good tolerance of the gel was reported by 95.22% of the respondents.
Conclusion. The daily use of Epigen Intim gel provides effective vulvovaginal hygiene with the reduction of frequency, duration and intensity of the discomfort with good tolerance.


glycyrrhizic acid
intimate hygiene
Epigen Intim


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Received 26.08.2020

Accepted 10.09.2020

About the Authors

Natalya I. Tapilskaya, MD, Professor, Leading Researcher of the Department Reproductive Technologies, the Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; Professor of the Department of Obstetrics and Gynecology, Saint Petersburg State Pediatric Medical University,
Ministry of Healthcare of the Russian Federation. E-mail: tapnatalia@yandex.ru. ORCID: 0000-0001-5309-0087.
199034, Russia, Saint-Petersburg, Mendeleyevskaya line, 3; 194100, Russia, Saint-Petersburg, Litovskaya str., 2.
Valentina F. Dolgushina, doctor of medical science, professor, Head of the Department of Obstetrics and Gynecology, South Ural State Medical University.
Tel.: +7(919)329-32-45. E-mail: dolgushinavf@yandex.ru 454092, Russia, Chelyabinsk, Vorovskiy str., 64.
Natalia V. Mingaleva, MD, professor, Kuban State Medical University. Krasnodar, Russia. Tel.: +7(861)222-05-43. E-mail: mingalevaN008@yandex.ru.
350063, Russia, Krasnodar, Mitrophan Sedin str., 4.

For citation: Tapilskaya N.I., Dolgushina V.F., Mingalyova N.V. Evaluation of the impact of intimate hygiene with Epigen Intim gel on discomfort in the area of external genital organs: results of an observational study.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2020; 9: 172-178 (in Russian).

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