Molecular mechanisms of and risk factors for endometriosis

DOI

https://dx.doi.org/10.18565/aig.2019.3.26-31

Ponomarenko I.V., Polonikov A.V., Churnosov M.I.
1 Belgorod State National Research University, Belgorod, Russia; 2 Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

The paper carries out a systems analysis of the data available in the current literature on the etiopathogenesis and risk factors of endometriosis. It considers the current data of foreign and Russian articles found in Pubmed on this topic. The main etiological hypotheses and molecular mechanisms of endometriosis are given; risk factors for its development are described. According to modern concepts, endometriosis is an etiologically heterogeneous disease, the basis of which is a complex set of hormonal, immunological, inflammatory, genetic, and epigenetic mechanisms. The risk factors for endometriosis are being actively studied, but the results obtained are ambiguous and often contradictory.

endometriosis

etiology

pathogenesis

risk factors

Full text (in Russian)

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Received 12.03.2018

Accepted 20.04.2018

Ponomarenko, Irina V., MD, associate professor of the Department of Biomedical Disciplines of the Medical Institute, Belgorod State National Research University.
Address: Russia, 308015, Belgorod, Pobedy str. 85. Tel.: +74722301383. E-mail: ponomarenko_i@bsu.edu.ru. https://orcid.org/0000-0002-5652-0166.
Polonikov, Alexey V., MD, Professor, Head of the Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, Ministry of Health of Russia.
Address: Russia, 305041, Kursk, K. Marx str. 3. Tel.: +74712588147. E-mail: polonikovav@kursksmu.net.
Churnosov, Mikhail I., MD, professor, head of the Department of Biomedical Disciplines Medical Faculty, Belgorod State National Research University.
Address: Russia, 308015, Belgorod, Pobedy str. 85. Tel.: +74722301383. E-mail: churnosov@bsu.edu.ru. http://orcid.org/0000-0003- 1254-6134.

For citation: Ponomarenko I.V., Polonikov A.V., Churnosov M.I. Molecular mechanisms of and risk factors for endometriosis. Akusherstvo i Ginekologiya/Obstetrics and Gynecology.2019; (3): 26-31. (in Russian)
https://dx.doi.org/10.18565/aig.2019.3.26-31

Molecular mechanisms of and risk factors for endometriosis

Ponomarenko I.V., Polonikov A.V., Churnosov M.I.

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