Giant ovarian mucinous cystadenoma in a 54-year-old woman

Chuprynin V.D., Buralkina N.A., Chursin V.V., Asaturova A.V., Katkova A.S., Zhurba A.Yu.

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia
Background. Ovarian cancer develops from benign tumors in 80% of cases during long-term follow-up. According to the literature, the incidence of giant ovarian cystadenoma is extremely low. There are difficulties in verifying these ovarian tumors.
Description. The paper describes a rare clinical case of a 54-year-old patient with giant ovarian cystadenoma. It depicts the patient’s clinical, medical history, laboratory, and instrumental data and demonstrates the technical complexities of surgery and the features of postoperative management.
Conclusion. The early diagnosis and timely treatment of ovarian tumors will be able to avoid technically difficult surgical interventions and to minimize postoperative complications, which will substantially improve the prognosis of the disease. Such operations should be performed by a surgeon having extensive surgical experience and high qualification.

Keywords

tumors of the uterine appendages
giant mucinous cystadenoma
ultrasound study
markers CA-125 and CA 19-9
magnetic resonance imaging (MRI)
anemia
laparotomy
adnexectomy

Supplementary Materials

  1. Fig. 1. Ultrasound of the pelvic organs and abdominal cavity
  2. Fig. 2. Progress: the capsule of formation is attached to the wound
  3. Fig. 3 (a, b). Course of operation: puncture of cystoma with fractional evacuation of contents - serous fluid - 8 vessels (32 liters)
  4. Fig. 4. Progress: an infiltrate involving ovarian tissue, sigmoid colon, bladder, clipping of the cystoma capsule
  5. Fig. 5. Macroperate: weight - 4,5 kg. Result of urgent histological examination: Mucinous ovarian cystadenoma
  6. Fig. 6. Type of patient before and after surgery. Stitching seam using a skin stapler
  7. Fig. 7. Result of histological conclusion: mucinous cystadenoma of the left ovary

References

1. Селезнева Н.Д. Железнов Б.И. Доброкачественные опухоли яичников. М.: Медицина; 1982. [Selezneva N.D. Zheleznov B.I. Benign tumors of the ovaries. Moscow: Medicine; 1982. (in Russian)]

2. Ашрафян Л.А., Ивашина С.В., Когай Н.В., Моцкобили Т.А., Бабаева Н.А., Огрызкова В.Л. Возможности соноэластометрии для дифференциальной диагностики доброкачественных и злокачественных опухолей яичников. Опухоли женской репродуктивной системы. 2012; 2: 55-9. [Ashrafyan L.A., Ivashina S.V., Kogai N.V., Motskobili T.A., Babayeva N.A., Ogryzkova V.L. Possibilities of sonoelastometry for differential diagnosis of benign and malignant ovarian tumors. Opuholi zhenskoy reproduktivnoy sistemyi. 2012; 2: 55-9. (in Russian)]

3. Урманчеева А.Ф., Кутушева Г.В., Ульрих Е.А. Опухоли яичника (клиника, диагностика и лечение). Пособие для врачей. СПб.: Издательство НЛ; 2012. 68с. [Urmancheeva A.F., Kutusheva G.V., Ulrich E.A. Tumors of the ovary (clinic, diagnosis and treatment). A manual for doctors. St. Petersburg: Publishing House NL; 2012. 68p. (in Russian)]

4. Lax S., Staebler A. Mucinous ovarian neoplasms. Prognostically mostly excellent, infrequently a wolf in sheep's clothing. Pathologe. 2014; 35(4): 327-35. doi: 10.1007/s00292-014-1912-4.

5. Боровкова Л.В., Першин Д.В., Загрядская Л.П. Диагностика опухолей яичников. Учебное пособие. Н. Новгород: Издательство НГМА; 2013. 45с. [Borovkova L.V., Pershin D.V., Zagryadskaya L.P. Diagnosis of ovarian tumors. Tutorial. N. Novgorod: Publisher NMMA; 2013. 45p. (in Russian)]

6. Кулаков В.И., Селезнева Н.Д., Белоглазова С.Е. Руководство по оперативной гинекологии. М.: МИА; 2006. 320с. [Kulakov V.I., Selezneva N.D., Beloglazova S.E. Manual on operative gynecology. Moscow: MIA; 2006. 320p. (in Russian)]

7. Bell D.A. Mucinous adenofibromas of the ovary. A report of 10 cases. Am. J. Surg. Pathol. 1991; 15(3): 227-32.

8. Бережная Н.М., Чехун В.Ф. Иммунология злокачественного роста. Киев: Наук думка; 2005. 791с. [Berezhnaya N.M., Chekhun V.F. Immunology of malignant growth. Kiev: Science of the Dumka; 2005. 791p. (in Russian)]

9. Sujatha V.V., Babu S.C. Giant ovarian serous cystadenoma in a postmenopausal woman: a case report. Cases J. 2009. 2: 7875.

10. Cîrstoiu M.M., Sajin M., Secară D.C., Munteanu O., Cîrstoiu F.C. Giant ovarian mucinous cystadenoma with borderline areas: a case report. J. Morphol. Embryol. 2014; 55(4):1443-7.

11. de Lima S.H., Dos Santos V.M., Darós A.C., Campos V.P., Modesto F.R. A 57-year-old Brazilian woman with a giant mucinous cystadenocarcinoma of the ovary: a case report. J. Med. Case Rep. 2014, 8: 82.

12. Temiz M., Aslan A., Gungoren A., Diner G., Karazincir S. A giant serous cystadenoma developing in an accessory ovary. Arch. Gynecol. Obstet. 2008; 278: 153-5.

13. Sharatz S.M., Treviño T.A., Rodriguez L., West J.H. Giant serous cystadenoma arising from an accessory ovary in a morbidly obese 11-year-old girl: a case report. J. Med. Case Rep. 2008; 2: 7.

Received 09.06.2017

Accepted 23.06.2017

About the Authors

Chuprynin Vladimir Dmitrievich, PhD, Head of the Department of General Surgery, Research Center of Obstetrics, Gynecology, and Perinatology,
Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina Str. 4. Tel.: +74954383575. E-mail: v_chuprynin@oparina4.ru
Buralkina Natalya Aleksandrovna, doctor of Medical Sciences, Senior Researcher, the second gynecological department, Research Center of Obstetrics,
Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina Str. 4. Tel.: +74954387833. E-mail: n_buralkina@oparina4.ru
Chursin Vyacheslav Vladimorovich, doctor surgeon of General Surgery, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina Str. 4. Tel.: +74954387833. E-mail:v_chursen@oparina4.ru
Alexandra Vyacheslavovna Asaturova, PhD, senior scientific researcher of pathology department, Research Center of Obstetrics, Gynecology and Perinatology,
Ministry of Health of Russia. 119997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954382311. E-mail: a_asaturova@oparina4.ru
Katkova A.S., clinical resident, Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia.
119997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74955314444. E-mail: a_katkova@oparina4.ru
Zhurba A.Yu., 5th year student of I.M. Sechenov First Moscow State Medical University.
119997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74955314444. E-mail: anastassia.zhurba@gmail.com

For citations: Chuprynin V.D., Buralkina N.A., Chursin V.V., Asaturova A.V., Katkova A.S., Zhurba A.Yu. Giant ovarian mucinous cystadenoma in a 54-year-old woman. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (1): 148-53. (in Russian)
https://dx.doi.org/10.18565/aig.2018.1.148-153

Similar Articles

By continuing to use our site, you consent to the processing of cookies that ensure the proper functioning of the site.