Infertility associated with female genital tuberculosis and familial Mediterranean fever
Background. The issues unveiling the features of the course of familial Mediterranean fever (FMF) concurrent with genital tuberculosis and their effects on fertility and pregnancy have recently become particularly relevant due to the spread of the disease outside the Mediterranean Basin.Sotsky P.O., Sotskaya O.L., Gevorkyan L.G., Atoyan S.A., Egiazaryan A.R., Papyan A.V., Safaryan M.D.
Description. Foreign and Russian studies on this topic were analyzed. The authors’ clinical example demonstrates the successful experience in recovering fertility in a 36-year-old female patient with infertility lasting 16 years. A relationship was found between long-term pelvic inflammatory diseases and the development of hyperplastic processes and ectopic pregnancy.
Conclusion. The phenotypic heterogeneity of FMF, comorbidity, and low compliance are the reasons for delayed diagnosis and restoration of fertility.
Keywords
genital tuberculosis
familial Mediterranean fever
infertility
ectopic pregnancy
polyposis
endometrial hyperplasia
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Received 16.05.2019
Accepted 21.06.2019
About the Authors
Pavel O. Sotskiy, PhD, obstetrician-gynecologist, Center of Medical Genetics and Primary Health Care, 34/3 Abovyan st, 0001,Yerevan, Armenia,Phone +37441188888. E-mail: pavel.sotskiy@gmail.com
Olga L. Sotskaya, PhD, Associate Professor, obstetrician-gynecologist, gynecologist-phthisiologist, Yerevan State Medical University after Mkhitar Heratsi, Koryun st, 0025, Yerevan, Armenia, Center of Medical Genetics and Primary Health Care, 34/3 Abovyan St, 0001, Yerevan, Armenia, Phone +37494008177, E-mail: olga.sotskajay@gmail.com
Lilit G. Gevoergyan, assistant in a department of phthisiology, phthisiologist, Yerevan State Medical University after Mkhitar Heratsi, Koryun st, 0025, Yerevan, Armenia, National tuberculosis center of the ministry of health, 10 Arzni Highway, 2204, Abovyan, Armenia. Phone+37491118906. E-mail: tiliagevorgyan@yahoo.com
Stepan A. Atoyan, PhD, general practitioner, Center of Medical Genetics and Primary Health Care, 34/3 Abovyan St, 0001, Yerevan, Armenia.
Phone: +37491229255, E-mail: stepanatoyan@gmail.com.
Anna R. Yeghiazaryan, geneticist, Center of Medical Genetics and Primary Health Care, 34/3 Abovyan St, 0001, Yerevan, Armenia. Phone:+37491357662,
E-mail: a.yeghiazaryan@gmail.ru
Andrey V. Papyan, MD, PhD, Pathological Anatomy and Clinical Morphology Department, Yerevan State Medical University after Mkhitar Heratsi, Koryun st,
0025, Yerevan, Armenia. Phone: +37493530205, andrew_papian@yahoo.com
Marina D. Safaryan, Honored Doctor of Armenia, Grand PhD, Professor, Head of department of phthisiology, Yerevan State Medical University after Mkhitar Heratsi, Koryun st, 0025, Yerevan, Armenia. Phone: +37491480321. E-mail: marina.safaryan@gmail.com
For citation: Sotsky P.O., Sotskaya O.L., Gevorkyan L.G., Atoyan S.A., Egiazaryan A.R., Papyan A.V., Safaryan M.D. Infertility associated with female genital tuberculosis and familial Mediterranean fever.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020; 3: 246-51. (In Russian).
https://dx.doi.org/10.18565/aig.2020.3.246-251
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