Pregnancy loss after intrauterine surgical treatment of twin-to-twin transfusion syndrome

17.02.2025
17:11
Russian scientists conducted a study aimed to analyze the association of preoperative cervical length shortening and its correction with termination of pregnancy in women with monochorionic twins after intrauterine twin-twin transfusion syndrome (TTTS) surgical treatment.

No correlation between cervical length shortening, methods of correction and adverse pregnancy outcomes was found in the study.

Current understanding of the pathogenesis of termination of pregnancy and preterm labor after fetoscopic laser coagulation is variable; suggested risk factors and current management tactics are controversial and not supported by conclusive evidence. The analysis of postoperative management strategies for patients with complicated monochorionic multiple pregnancies should be evaluated in randomized trials, which can improve overall perinatal outcomes, reduce neonatal mortality and morbidity and be the next step in making fetoscopic laser surgery for TTTS more effective.

Gladkova K.A., Sakalo V.А. Pregnancy loss after intrauterine surgical treatment of twin-to-twin transfusion syndrome

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