Influence of perinatal factors on neonatal outcomes in Rh(D)-mediated hemolytic disease of the fetus and newborn treated with intrauterine transfusion
07.11.2024
14:52
Russian researchers conduct the study aimed to explore neonatal outcomes amongst patients with Rh(D)-mediated HDFN treated with intrauterine transfusions (IUT) and evaluate the effect of perinatal factors on neonatal morbidity and mortality.
The results showed, that hydrops fetalis continues to be a leading perinatal factor negatively influencing neonatal survival and neurologic outcomes. The absence of positive dynamics of pre-IUT fetal Hb reflects a significantly higher risk of hydrops, severe perinatal brain injury, and lethal outcomes.
