Assessment of embryological outcomes in ivf programs for patients of different age groups based on AMH levels
25.07.2025
09:27
Russian researchers from the Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, conducted a study aimed to evaluate embryological outcomes of IVF programs by examining the number of high-quality blastocysts in relation to AMH levels across different patient age groups.
Even when AMH levels in young women and older patients are comparable, the proportion of good-quality blastocysts significantly decreases with age, approaching zero after the age of 40 years. This decline is likely due to the quality of oocytes, aneuploidy of embryos, and developmental disorders in patients of late reproductive ages. In contrast, young patients can still obtain good-quality embryos even with reduced ovarian reserve indicators. Therefore, the authors suggest implementing IVF programs for younger patients, including those with diminished ovarian reserves, and integrating this approach into state-supported guarantees for the application of ART.
