Current views on microbiota in gynecology

Tabeeva G.I., Dumanovskaya M.R., Chernukha G.E., Priputnevich T.V.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow, Russia
The paper reviews publications on the microbiota state in endometriosis, various endometrial abnormalities (endometrial polyps, endometrial hyperplasia, chronic endometritis), and endometrial cancer, as well as in infertility. The investigators identified certain microorganisms that can be potentially considered as predictors for the effectiveness of assisted reproductive technology (ART) programs. An analysis of the literature proves the relationship of microbiome disorders to the development of benign and malignant diseases. The investigation results raise questions regarding the molecular mechanisms of tissue and cellular homeostatic disorders between the microbiota and the human body in various pathological processes. These support the expediency of conducting investigations in this area.

Keywords

microbiota
microbiome
endometrium
endometrial hyperplastic processes
infertility
endometriosis

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Received 14.08.2019

Accepted 04.10.2019

About the Authors

Gyuzyal I. Tabeeva, Ph. D., senior researcher of the Department of gynecological endocrinology of the National medical research center of obstetrics, gynecology and Perinatology named after academician V. I. Kulakov of the Ministry of health of the Russian Federation, Moscow. E-mail: doctor.gtab@gmail.com
117997 Russia, Moscow, Academician Oparin str., 4.
Madina R. Dumanovskaya, Ph. D., researcher of the Department of gynecological endocrinology, National medical research center of obstetrics, gynecology and
Perinatology named after academician V. I. Kulakov health Ministry of the Russian Federation, Moscow. 117997 Russia, Moscow, Academician Oparin str., 4.
Galina E. Chernukha, MD, Professor, head of the Department of gynecological endocrinology of the National medical research center of obstetrics, gynecology and Perinatology named after academician V. I. Kulakov of the Ministry of health of the Russian Federation, Moscow. 117997 Russia, Moscow, Academician Oparin str., 4.
Tatyana V. Priputnevich, doctor of medical Sciences, head of Department of Microbiology, clinical pharmacology and epidemiology, National medical research center
of obstetrics, gynecology and Perinatology named after academician V. I. Kulakov health Ministry of the Russian Federation.
117997 Russia, Moscow, Academician Oparin str., 4.

For citation: Tabeeva G.I., Dumanovskaya M.R., Chernukha G.E., Priputnevich T.V. Current views on microbiota in gynecology.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020;2: 38-44 (In Russian).
https://dx.doi.org/10.18565/aig.2020.2.38-44

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