The novel coronavirus infection (COVID-19) concurrent with pseudomembranous colitis in the early postpartum period: a clinical case
Background: Women are most at risk for Clostridium difficile infection in the early postpartum period. Clostridium difficile-associated colitis may be mistaken for the intestinal form of COVID-19 during the ongoing novel coronavirus infection pandemic.Shklyaev A.E., Bessonov A.G., Chushyalova D.A., Mikhailova M.D., Meleshkina M.V.
Case report: The paper describes a clinical case of a female patient diagnosed with the novel coronavirus infection and Clostridium difficile-associated pseudomembranous colitis in the early postpartum period. It depicts the diagnosis and treatment of the identified concurrent pathology. It demonstrates data from of an endoscopic examination of the colon and spiral computed tomography of the chest and provides laboratory confirmation of the infectious etiology of comorbidity. There are data available in the literature on the high rate and recurrent course of pseudomembranous colitis in the early postpartum period. It is noted that timely C. difficile eradication and pathogenetic treatment for the novel coronavirus infection allow relief of clinical symptoms.
Conclusion: The case of the novel coronavirus infection concurrent with Clostridium difficile-associated pseudomembranous colitis in the early postpartum period is of interest in connection with the need for differential diagnosis of the etiology of diarrheal syndrome, the precise identification of which determines the further tactics of patient management and the nature of anti-epidemic measures.
Keywords
Clostridium difficile-associated infection
postpartum period
antibiotic therapy
exotoxin A and B
C. difficile
coronavirus infection
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Received 18.03.2021
Accepted 08.09.2021
About the Authors
Alexey E. Shklyaev, Dr. Med. Sci., Professor, Professor of the Department of Faculty Therapy with courses in Endocrinology and Hematology, Izhevsk State Medical Academy, Ministry of Health of the Russian Federation, +7(3412)52-62-01, shklyaevaleksey@gmail.com,https://orcid.org/0000-0003-4479-508X, 426034, Russia, Izhevsk, Kommunarov str., 281.
Alexey G. Bessonov, PhD, Head of the Gastroenterology Department, the First Republican Clinical Hospital, Ministry of Health of UR,
+7(3412)46-52-92, 426039, Russia, Izhevsk, Votkinskoe shosse, 57.
Darya A. Chushyalova, student, Izhevsk State Medical Academy, Ministry of Health of the Russian Federation, +7(919)911-39-29, chushyalowa@yandex.ru,
https://orcid.org/0000-0002-5062-1716, 426034, Russia, Izhevsk, Kommunarov str., 281.
Maria D. Mikhailova, PhD, Assistant of the Department of Faculty Therapy with courses of Endocrinology and Hematology, Izhevsk State Medical Academy,
Ministry of Health of the Russian Federation, +7(3412)52-62-01, 426034, Russia, Izhevsk, Kommunarov str., 281.
Maria V. Meleshkina, gastroenterologist, the First Republican Clinical Hospital, Ministry of Health of UR, +7(3412)46-52-92, 426039, Russia, Izhevsk, Votkinskoe shosse, 57.
Authors' contributions: Shklyaev A.E., Bessonov A.G., Chushyalova D.A., Mikhailova M.D., Meleshkina M.V. – material collection and processing; Shklyaev A.E., Chushyalova D.A. – writing the text; Shklyaev A.E. – editing.
Conflicts of interest: The authors declare that there are no possible conflicts of interest.
Funding: The article has been prepared without sponsorship.
Patient Consent for Publication: The patient provided informed consent for the publication of her data.
Authors' Data Sharing Statement: The data supporting the findings of this study are available on request from the corresponding author after approval from the principal investigator.
For citation: Shklyaev A.E., Bessonov A.G., Chushyalova D.A., Mikhailova M.D., Meleshkina M.V. The novel coronavirus infection (COVID-19) concurrent with pseudomembranous colitis in the early postpartum period: a clinical case.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2021; 9: 232-236 (in Russian)
https://dx.doi.org/10.18565/aig.2021.9.232-236
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