Advantages of using a rapid diagnostic test system to determine placental α1-microglobulin in the cervical contents for identification of incipient/threatened preterm labor
Objective. To determine whether a combined use of a test system to determine the content of placental α-microglobulin (PAMG)-1 in cervical contents and ultrasonic cervicometry (UZC) can improve the identification of spontaneous preterm births.Fatkullin I.F., Akhmetgaliev A.R., Munavirova A.A., Fatkullin F.I.
Subjects and methods. A group included 172 pregnant women with clinical presentations of threatened/incipient preterm labor at 24-33 weeks’ gestation.
Results. There is a strong relationship between the positive test result and the likelihood of delivery on the following 0-14 days.
Conclusion. The combined use of ultrasound cervicometry and PAMG-1 test leads to an increase in their diagnostic efficiencies.
Keywords
diagnosis of preterm labor
placental α1-microglobulin
cervicometry
uterine cervical length
Supplementary Materials
- Table 1. Characteristics of the study group of pregnant women ( n = 172)
- Table 2. The frequency of premature births , depending on the time of onset of labor, gestational age, cervical length and test result
- Table 3. Calculation of statistical indicators to test for determination ofplacental α-th and -1 microglobulin in cervico-vaginal secretions andultrasound cervicometry
- Figure. Research Flowchart
References
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Received 30.11.2017
Accepted 22.12.2017
About the Authors
Fatkullin Ildar Faridovich, MD, Professor, Head of the Department of Obstetrics and Gynecology № 2 of Kazan State Medical University, Ministry of Health of Russia.420012, Russia, Kazan, Butlerova str. 49
Ahmetgaliev Arthur Rinatovich, assistent professor of the Department of Obstetrics and Gynecology № 2 of Kazan State Medical University, Ministry of Health of Russia. 420012, Russia, Kazan, Butlerova str. 49
Munavirova Adelia Azatovna, resident of the Department of Obstetrics and Gynecology № 2 of Kazan State Medical University, Ministry of Health of Russia.
420012, Russia, Kazan, Butlerova str. 49
Fatkullin Farid Ildarovich, Ph.D., associate professor of obstetrics and Gynecology № 2 of Kazan State Medical University, Ministry of Health of Russia;
head of the Department of Pregnancy Pathology, City Clinical Hospital Seven. 420012, Russia, Kazan, Butlerova str. 49
For citations: Fatkullin I.F., Akhmetgaliev A.R., Munavirova A.A., Fatkullin F.I. Advantages of using a rapid diagnostic test system to determine placental α1-microglobulin in the cervical contents for identification of incipient/threatened preterm labor.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (1): 62-8. (in Russian)
https://dx.doi.org/10.18565/aig.2018.1.62-68
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