Impaired autonomic regulation in pregnant women with iron deficiency anemia and ways of its correction
Objective. To investigate the corrective properties of medical ozone, ozone, and an iron-containing supplement and only an iron-containing supplement in the combination treatment of iron deficiency anemia (IDA) in pregnant women in relation to the functional state of the autonomic nervous system.Sheveleva G.A., Fedorova T.A., Dubrovina N.V., Sokur T.N., Bakuridze E.M.
Material and methods. Cardiointervalographic analysis was used to study the specific features of autonomic regulation in 60 pregnant women (divided into 3 groups) with mild and moderate IDA in the second (before treatment) and third (after treatment) trimesters of pregnancy.
Results. The use of ozone, or ozone in combination with an iron-containing supplement, contributes to a substantial improvement in the autonomic balance of regulating systems in the majority of patients and suggests that it is expedient to incorporate ozone in the combination therapy for IDA. The iron supplement used alone was ineffective and depended on the type of autonomic homeostasis in women.
Keywords
iron deficiency anemia in pregnant women
ozone
iron-containing supplement
cardiointervalography
regulatory mechanisms of the autonomic nervous system
Supplementary Materials
- Table 1. Indices of cardiointervalography at rest in pregnant women with IDA before and after ozone therapy
- Table 2. Indices of cardiointervalography at rest in pregnant women with IDA before and after ozone therapy in combination with iron-containing drug
- Table 3. Parameters of cardiointervalography in pregnant women with IDA at rest before and after therapy with iron-containing drug
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Received 08.11.2016
Accepted 11.11.2016
About the Authors
Galina Sheveleva, Doctor of Biological Sciences, Consultant, Department of Transfusion Immunology and Blood Preparation, Research Center of Obstetrics,Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79165180678. E-mail: shewelewa.gal@yandex.ru
Tatyana Fedorova, doctor of medical sciences, professor, head of the transfusiology and extracorporeal hemocorrection department, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954387135. E-mail: tfedorova 1@mail.ru
Natalia Dubrovina, Ph.D., Research Fellow, Obstetric Observational Unit, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954380988. E-mail: n_dubrovina@oparina4.ru
Tatyana Sokur, doctor of medical sciences, leading researcher, 1st obstetrical department, Research Center of Obstetrics, Gynecology, and Perinatology,
Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954380788. E-mail: t_sokur@oparina4.ru
Eteri Bakuridze, Candidate of Medical Sciences, Head of Clinical Work, Transfusiology and Extracorporeal Hemocorrection Department, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954387135. E-mail: e_bakuridze@oparina4.ru
For citations: Sheveleva G.A., Fedorova T.A., Dubrovina N.V., Sokur T.N., Bakuridze E.M. Impaired autonomic regulation in pregnant women with iron deficiency anemia and ways of its correction. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (6): 35-40. (in Russian)
http://dx.doi.org/10.18565/aig.2017.6.35-40
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