A new perspective on the potential of IСOONE therapy in gynecological practice

Saidova А.S., Apolikhina I.A., Boldyreva А.А., Grinina О.V., Babayan М.G.

1) Academician V.I. Kulakov National Medical Research Centre for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia; 2) I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia

In recent years, there has been a significant increase in the use of high-tech, non-invasive methods in medical rehabilitation, physiotherapy, and aesthetic medicine. This is largely due to the desire to use gentle yet clinically effective approaches that aim to repair tissues, improve microcirculation, and correct fibrotic changes, without the need for pharmacological or surgical interventions. One of these methods is the Roboderm ICOONE Laser technology, which combines fractional vacuum exposure with low-intensity laser radiation (915 nm) and LED therapy (650 nm).
This paper examines the proposed mechanisms of action of ICOONE therapy and summarizes the data obtained from clinical observations in various pathological conditions. The method is based on multimicroalveolar stimulation (MMAS), which uses a fractional vacuum to create multiple zones of localized rarefaction evenly distributed over the surface of the tissue. This creates a gentle and controlled mechanical effect. In combination with low-intensity light exposure, this can help activate metabolic processes, improve microcirculation, normalize lymphatic outflow, and stimulate reparative processes in connective tissue. The complex effect can influence the skin, subcutaneous fat and connective tissue structures, without causing any damage to the tissue.
This technique can be considered as part of a complex therapy for conditions that are accompanied by impaired microcirculation and lymphovenous drainage, as well as in rehabilitation programs for women. It can be used during postpartum recovery, for the correction of postoperative scars, in women after cesarean section and in peri- and postmenopausal patients. Of particular interest is the possibility of using the method in patients with overweight and functional disorders affecting the quality of life.
Conclusion: The results of the analysis of the available data indicate the potential clinical significance of Icoone® therapy in gynecological practice. The use of this method is associated with improvements in tissue nutrition, a decrease in the severity of swelling, improvements in the characteristics of scar tissue and the subjective well-being of patients. According to published observations, the procedures have been shown to be well-tolerated, safe, and allow for individualized selection of exposure parameters. However, further clinical studies are necessary to assess long-term outcomes and determine optimal treatment regimens in order to develop standardized treatment protocols.

Authors’ contributions: Saidova A.S. – developing the concept of the study, obtaining data for analysis, review of publications on the subject of the article, statistical analysis of the obtained data, writing the text of the manuscript, editing the article; Boldyreva A.A., Grinina O.V., Babayan M.G. – review of publications on the subject of the article, statistical analysis of the obtained data, writing the text of the manuscript; Apolikhina I.A. – editing and final approval of the version for publication.
Conflicts of interest: The authors declare that there are no conflicts of interest.
Funding: The study was conducted without sponsorship.
For citation: Saidova А.S., Apolikhina I.A., Boldyreva А.А., Grinina О.V., Babayan М.G. A new perspective on
the potential of ICOONE therapy in gynecological practice.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2026; (2): 158-164 (in Russian)
https://dx.doi.org/10.18565/aig.2026.49

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About the Authors

Aina S. Saidova, PhD, obstetrician-gynecologist at the Department of Aesthetic Gynecology and Rehabilitation, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, a_saidova@oparina4.ru, https:/orcid.org/0000-0003-3473-3109
Inna A. Apolikhina, Dr. Med. Sci., Professor, Head of the Department of Aesthetic Gynecology and Rehabilitation, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4; Professor at the Department of Obstetrics, Gynecology, Perinatology, and Reproductology, Institute of Professional Education, I.M. Sechenov First MSMU, Ministry of Health of Russia (Sechenov University), 119048, Russia, Moscow, Trubetskaya str., 8-2, apolikhina@inbox.ru,
https://orcid.org/0000-0002-4581-6295
Anastasia A. Boldyreva, obstetrician-gynecologist, Junior Researcher at the Department of Aesthetic Gynecology and Rehabilitation, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, boldyreva.anastasi@gmail.com, https://orcid.org/0009-0003-4679-3229
Olesya V. Grinina, resident, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, leska2312@gmail.com
Marine G. Babayan, resident, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, marina1999babayan@mail.ru,
https://orcid.org/0009-0003-1973-6712