About
The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
ArchiveEthical StandardsSubscription
For authors
InstructionsInformed consent policyContract offerEASE GuidelinesICJME CriteriaWAME Recommendations on ChatGPT and Chatbots in Relation to Scholarly Publications
Reviewing
Procedure for reviewingReviewers 2023-2024
About
The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
ArchiveEthical StandardsSubscription
For authors
InstructionsInformed consent policyContract offerEASE GuidelinesICJME CriteriaWAME Recommendations on ChatGPT and Chatbots in Relation to Scholarly Publications
Reviewing
Procedure for reviewingReviewers 2023-2024
Logout
Obstetrics and Gynegology2024№10
Rare benign vulvar tumors

Rare benign vulvar tumors

DOI
https://dx.doi.org/10.18565/aig.2024.134

Zharov A.V., Slashcheva M.V., Kolesnikova E.V.

Kuban State Medical University, Ministry of Health of Russia, Krasnodar, Russia

To optimize the surgical treatment of patients with rare benign vulvar tumors on the basis of clinical characteristics of the disease.
This article presents clinical cases of benign vulvar tumors such as superficial angiomyxoma, papillary hidradenoma, fibroangiolipoma, and vulvar fibropapilloma.
The article describes patients’ complaints, case history, clinical picture, and the type of pathologic focus in the vulva area. It emphasizes the main clinical characteristics which are necessary for timely diagnosis of the disease.
Rare benign vulvar tumors are often difficult to diagnose. A thorough examination of the inguinal-femoral lymph nodes is essential for an accurate diagnosis. The absence of enlarged lymph nodes, absence of tumor infiltration of the underlying tissues, expansive growth, and clear boundaries with healthy tissues are indicative of a benign tumor. The doctor can frequently be confused by the large size of the mass; however, a long history of the disease in combination with the above-mentioned characteristics also suggests that the process is benign. Meanwhile, the presence of enlarged, dense, painless regional lymph nodes can be indicative of a malignant tumor, even if the primary focus is small.
Conclusion: When choosing a surgical and postoperative treatment option, one should consult the physician and the morphologist; additional clinical data presented to the morphologist can help make the final diagnosis easier and exclude suboptimal surgery.

Authors’ contributions: Zharov A.V. – developing the concept and design of the study, collecting and processing the material, writing the text, editing the text; Slashcheva M.V. – developing the concept and design of the study, collecting and processing the material, writing the text; Kolesnikova E.V. – processing the material, editing the text.
Conflicts of interest: Authors declare lack of the possible conflicts of interest.
Funding: The study was conducted without sponsorship.
Patient Consent for Publication: The patients provided an informed consent for the publication of their data and and associated images.
For citation: Zharov A.V., Slashcheva M.V., Kolesnikova E.V. Rare benign vulvar tumors.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2024; (10): 167-172 (in Russian)
https://dx.doi.org/10.18565/aig.2024.134

Keywords

vulvar tumor
superficial angiomyxoma
papillary hidradenoma
fibroangiolipoma
fibropapilloma
Full text (in Russian)

References

  1. Сулейманова А.М., Качанов Д.Ю. Отчет о проведении Первого международного конгресса по редким опухолям «Редкие опухоли. Фундаментальные и клинические достижения». Российский журнал детской гематологии и онкологии. 2019; 6(3): 103-4. [Suleimanova A.M., Kachanov D.Yu. Report on the First International Congress on Rare Tumors “Rare Tumors. Fundamental and Clinical Achievements”. Russian Journal of Pediatric Hematology and Oncology. 2019; 6(3): 103-4. (in Russian)].
  2. Fetsch J.F., Laskin W.B., Tavassoli F.A. Superficial angiomyxoma (cutaneous myxoma): a clinicopathologic study of 17 cases arising in the genital region. Int. J. Gynecol. Pathol. 1997; 16(4): 325-34. https://dx.doi.org/10.1097/00004347-199710000-00006.
  3. Жаров А.В., Колесникова Е.В., Пенжоян Г.А., Дряева Л.Г. Редкие опухолеподобные образования вульвы. Акушерство и гинекология. 2021; 6: 192-7. [Zharov A.V., Kolesnikova E.V., Penzhoyan G.A., Dryaeva L.G. Rare tumor-like masses in the vulva. Obstetrics and Gynecology. 2021; (6): 192-7. (in Russian)]. https://dx.doi.org/10.18565/aig.2021.6.192-197.
  4. Tosti G., Salvini C., Barisani A., Grazi R., Pirola S., Cantisani C. et al. Vulval hidradenoma papilliferum: a clinical and dermoscopic study. Clin. Exp. Dermatol. 2020; 45(8): 1035-9. https://dx.doi.org/10.1111/ced.14254.
  5. Жаров А.В., Колесникова Е.В., Пенжоян Г.А. Редкие опухоли вульвы с агрессивным характером клинического течения. Акушерство и гинекология. 2021; 9: 127-33. [Zharov A.V., Kolesnikova E.V., Penzhoyan G.A. Rare vulvar tumors with their aggressive clinical course. Obstetrics and Gynecology. 2021; (9): 127-33. (in Russian)]. https://dx.doi.org/10.18565/aig.2021.9.127-133.
  6. Жаров А.В., Колесникова Е.В., Пенжоян Г.А. Проблемы диагностики и лечения больных с фоновыми процессами и опухолевой патологией вульвы. Кубанский научный медицинский вестник. 2018; 25(6): 78-82. [Zarov A.V., Kolesnikova E.V., Penzhoyan G.A. Problems of diagnosis and treatment of patients with background processes and tumor pathology of the vulva. Kuban Scientific Medical Bulletin. 2018; 25(6): 78-82. (in Russian)]. https://dx.doi.org/10.25207/1608-6228-2018-25-6-78-82.
  7. Ros Briones R., Arredondo Montero J., Bronte Anaut M., Hernández-Martín S., Guarch Troyas R. Pediatric vulvar superficial angiomyxoma: a case report with clinical, radiological, and anatomopathological characterization and a comprehensive review of the literature. Int. J. Surg. Pathol. 2023; 31(5): 852-60. https://dx.doi.org/10.1177/10668969221140381.
  8. Mehrotra K., Bhandari M., Khullar G., Sharma S. Large superficial angiomyxoma of the vulva-report of two cases with varied clinical presentation. Indian Dermatol. Online J. 2021; 12(4): 605-7. https://dx.doi.org/10.4103/idoj.IDOJ_489_20.
  9. Duhan N., Kalra R., Singh S., Rajotia N. Hidradenoma papilliferum of the vulva: case report and review of literature. Arch. Gynecol. Obstet. 2011; 284(4): 1015-7. https://dx.doi.org/10.1007/s00404-010-1784-7.
  10. Ламоткин И.А. Клиническая дерматоонкология. Aтлас. М.: БИНОМ. Лаборатория знаний; 2011. 499с. [Lamotkin I.A. Klinicheskaya dermatoonkologiya. Atlas. Moscow: BINOM. Laboratoriya znanii; 2011. 499p. (in Russian)].
  11. Rodríguez-Vázquez M., García-Arpa M., Delgado M., Cortina P., Vera E., Romero G. Angiomixoma superficial [Superficial angiomyxoma]. Actas Dermosifiliogr. 2005; 96(5): 311-4. (in Spanish). https://dx.doi.org/10.1016/s0001-7310(05)75061-4.
  12. Navea O.V., Navea M.B., Dela Fuente R. Superficial angiomyxoma in anuncommon area: a case report. Cureus. 2023; 15(12): e50286. https://dx.doi.org/10.7759/cureus.50286.
  13. Lee C.C., Chen Y.L., Liau J.Y., Chen C.A., Cheng W.F. Superficial angiomyxoma on the vulva of an adolescent. Taiwan. J. Obstet. Gynecol. 2014; 53(1): 104-6. https://dx.doi.org/10.1016/j.tjog.2013.08.001.
  14. Navitski A., Adams L., Brzezinska B.N., Suhner J., Sliker T., Moideen P. et al. A tale of two vulvar angiomyxomas: two cases and review of literature. Gynecol. Oncol. Rep. 2023; 47: 101204. https://dx.doi.org/10.1016/j.gore.2023.101204.
  15. Goyal L.D., Garg P., Badyal R., Bhalla S. Aggressive (deep) angiomyxoma of the vulva: a case report. J. Med. Case Rep. 2022; 16(1): 71. https://dx.doi.org/10.1186/s13256-022-03284-z.
  16. Werth R. Anatomy of cysts of the vulva. Zentralbl. Gynacol. 1878; 22: 513-6.
  17. Elouarradi R., Hocar O. Hidradénome papillifère [Hidradenoma papilliferum]. Pan. Afr. Med. J. 2014; 17: 274. (in French). https://dx.doi.org/10.11604/pamj.2014.17.274.4177.
  18. Пахарукова М.И., Вайнберг Э.И., Лысак Е.Е. Сложности морфологической диагностики гидраденомы вульвы. Новости клинической цитологии. 2019; 23(3): 29-30. [Pakharukova M.I., Vainberg E.I., Lysak E.E. Difficulties in the morphological diagnosis of vulvar hydroadenoma. Russian News of Clinical Cytology. 2019; 23(3): 29-30. (in Russian)]. https://dx.doi.org/10.24411/1562-4943-2019-10305.
  19. Kennelly M.J., Grossman H.B., Cho K.J. Outcome analysis of 42 cases of renal angiomyolipoma. J. Urol. 1994; 152(6 Pt. 1): 1988-91. https://dx.doi.org/10.1016/s0022-5347(17)32286-3.
  20. Каприн А.Д., Костин А.А., Федотов Е.В., Семин А.В., Глебушкин Р.С., Нестеров П.В., Нечай В.В., Лупашко Д.Г. Ангиомиолипома почки (описание клинического случая). Онкоурология. 2013; 9(1): 77-81. [Kaprin A.D., Kostin A.A., Fedotov E.V., Semin A.V., Glebushkin R.S., Nesterov P.V., Nechai V.V., Lupashko D.G. Renal angiomyolipoma (a case report). Cancer Urology. 2013; 9(1): 77-81. (in Russian)]. https://dx.doi.org/10.17650/1726-9776-2013-9-1-77-81.
  21. Steiner M.S., Goldman S.M., Fishman E.K., Marshall F.F. The natural history of renal angiomyolipoma. J. Urol. 1993; 150(6): 1782-6. https://dx.doi.org/10.1016/s0022-5347(17)35895-0.
  22. Sengupta S., Bhattacharya M., Datta P. Angiolipoma of the labia majora. J. Indian Med. Assoc. 1976; 66(2): 40-1.
  23. Bahadur A., Mundhra R., Heda A., Singh A. Large vulvar fibroepithelial polyp and review of differentials. BMJ Case Rep. 2024; 17(2): e259389. https://dx.doi.org/10.1136/bcr-2023-259389.

Received 03.06.2024

Accepted 01.08.2024

About the Authors

Alexander V. Zharov, Dr. Med. Sci., Professor, Department of Obstetrics, Gynecology and Perinatology of the FPC and PPP, Kuban State Medical University,
Ministry of Health of Russian Federation, 350063, Russia, Krasnodar, Sedin str., 4, +7(918)960-25-38, Zharov.1966@yandex.ru, https://orcid.org/0000-0002-5460-5959
Marina V. Slashcheva, PhD student at the Department of Obstetrics, Gynecology and Perinatology of the FPC and PPP, Kuban State Medical University, Ministry of Health
of Russia, 350063, Russia, Krasnodar, Sedin str., 4, +7(912)323-79-28, Marina98@inbox.ru, https://orcid.org/0009-0002-4047-1408
Ekaterina V. Kolesnikova, PhD, Associate Professor, Department of Obstetrics, Gynecology and Perinatology of the FPC and PPP, Kuban State Medical University,
Ministry of Health of Russia, 350063, Russia, Krasnodar, Sedin str., 4, +7(964)914-09-42, Jokagyno@rambler.ru, https://orcid.org/0000-0002-6537-2572
Corresponding author: Marina V. Slashcheva, Marina98@inbox.ru
By continuing to use our site, you consent to the processing of cookies that ensure the proper functioning of the site.