Predictors of infertility

Barinova E.R., Aruytin D.G.

1) Medical Institute, Peoples’ Friendship University of Russia (RUDN University), Moscow, Russia; 2) N.E. Bauman City Clinical Hospital No. 29, Moscow City Healthcare Department, Moscow, Russia
Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12 months of regular unprotected sexual life. Infertility tends to become another pandemic of the modern world. According to some estimates, the frequency of infertile marriages ranges 10–25% (from 48 to 180 million). Such couples face adverse consequences for physical and mental health, financial difficulties, a serious social stigma, an increased risk of domestic violence, and instability in marriage. The evaluation of the female factor infertility has been traditionally the driving force in the examination of infertility.
Although men and women are equally susceptible to infertility; however, women bear a greater social burden, especially in the societies where identity and social value are closely related to the ability to give birth to babies. The age-related decline in female fertility is of serious concern; moreover, the decision about pregnancy is frequently made at a later age. Therefore, the study of the causes of infertility development is extremely important and a review of the current studies on this topic seems relevant. This review considers the most common causes of infertility, such as ovulatory dysfunctions, male infertility, tubal diseases, lifestyle (smoking, obesity), environmental factors, abnormalities of the uterus and cervix uteri, as well as endometriosis.
Conclusion: Infertility is a multifactorial disease that requires further investigation and solution of this problem to achieve the main result – to overcome infertility. Despite advances in the modern diagnosis and treatment of infertility, the number of infertile couples is growing every year. Therefore, female patients of any age need a personalized treatment approach. It should be noted that modern trends in medicine are aimed at the prediction and prevention of diseases that can lead to menacing complications, including infertility.

Authors' contributions: Barinova E.K. – writing the text; Aryutin D.G. – editing the text; Aryutin D.G., Barinova E.K. – concept and design.
Conflicts of interest: The authors declare that there is no potential interest conflict requiring disclosure in this article.
Funding: The investigation has not been sponsored.
For citation: Barinova E.K., Aryutin D.G. Predictors of infertility.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2023; (4): 178-183 (in Russian)
https://dx.doi.org/10.18565/aig.2023.66

Keywords

infertility
risk factors

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Received 15.03.2023

Accepted 17.04.2023

About the Authors

Ebecha K. Barinova, graduate student of the Department of Obstetrics and Gynecology with a course of perinatology, RUDN University, +7(926)695-40-73,
barinovaek@inbox.ru, https://orcid.org/0000-0001-8282-6508, 117198, Russia, Moscow, Miklukho-Maklaya str., 8.
Dmitry G. Aryutin, Ph.D., Head of the Gynecological Department, N.E. Bauman City Clinical Hospital No. 29, Moscow Healthcare Department; Associate Professor at the Department of Obstetrics and Gynecology with a course of perinatology, RUDN University, +7(903)772-95-38, aryutin@mail.ru, https://orcid.org/0000-0003-0258-8445, 111020, Russia, Moscow, Hospital sqr., 2.

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