Cancers during pregnancy

Makieva M.I., Tsoi T.A., Kosolapova Yu.A.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia
The paper considers the impact of cancer on pregnancy and fetal health. It describes the impact of chemotherapy on the course of pregnancy, the fetus and the state of the immune system in the pregnant woman and fetus, the risks of central nervous system and cardiovascular system diseases, and the general health and physical development of newborn infants. What is the immune status in a newborn of mothers who received chemotherapy during pregnancy, vaccination in the first day of life for children whose mothers have received chemotherapy during pregnancy. The paper shows pregnancy management tactics, optimal terms for prescribing and discontinuing chemotherapy; pregnancy outcomes after early and delayed initiation of therapy. There are the latest results of studies to optimize delivery terms for both the mother and fetus.

Keywords

cancer during pregnancy
chemotherapy and fetus
chemotherapy regimens during pregnancy
impact of chemotherapy on the fetus
immune status in the newborn from mothers receiving chemotherapy during pregnancy
paclitaxel
doxorubicin
vincristine
vinblastine
rituximab
5-fluorouracil
doxorubicin
cyclophosphamide

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Received 01.10.2019

Accepted 04.10.2019

About the Authors

Mzia I. Makieva, neonatologist, pediatrician, head of the department of newborns №2 of FSBI NMIIC AGP them. Academician V.I. Kulakova Ministry of Health of Russia. Phone: +7 (495)438-11-83. E-mail: m_makieva@oparina4.ru Address: 117997, Russia, Moscow, ul. Academician Oparin, d. 4.
Tatyana A. Tsoy, neonatologist, neonatal unit Academician V.I. Kulakova Ministry of Health of Russia. Phone: +7 (495)438-11-83. E-mail: t_tsoy@oparina4.ru
Address: 117997, Russia, Moscow, ul. Academician Oparin, d. 4.
Julia A. Kosolapova, neonatologist, junior researcher neonatal unit Academician V.I. Kulakova Ministry of Health of Russia.
Phone: +7 (495)438-11-83. E-mail: yuliya-kibalnikova@yandex.ru Address: 117997, Russia, Moscow, ul. Academician Oparin, d. 4.

For citation: Makieva M.I., Tsoi T.A., Kosolapova Yu.A. Cancers during pregnancy.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020;2: 5-12 (In Russian).
https://dx.doi.org/10.18565/aig.2020.2. 5-12
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