Magnetic resonance imaging in the diagnosis of peritoneal carcinomatosis in disseminated ovarian cancer

Syrkashev E.M., Solopova A.E., Kulabukhova E.A.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russian Federation
Ovarian cancer is one of the most common malignant neoplasms of the female reproductive system. The overwhelming majority of cases were diagnosed with advanced stages of the process in the presence of peritoneal carcinomatosis and parenchymal metastases. The extent of the disease is the most important prognostic factor. The 5-year survival rate for all types of ovarian cancer is 46% and varies substantially according to the stage: 92% for a localized process, 75% for locally advanced one, and only 29% among patients with distant metastases. The localization of secondary changes and the degree of damage considerably affect the likelihood of successful cytoreductive surgery that in turn determines the long-term prognosis of the disease. Multislice computed tomography (MSCT) is the standard for the preoperative staging of ovarian cancer. The sensitivity and specificity of MSCT depend primarily on the size and location of peritoneal implants that have a similar density to adjacent unaltered structures. This problem becomes especially urgent in the absence of ascites. The potential of multiparametric MRI (mp-MRI) to improve the accuracy of staging of disseminated ovarian cancer and a response to the treatment performed is now increasingly discussed. This publication describes in detail the semiotics of disseminated ovarian cancer, presents the authors’ own verified clinical cases, and analyzes the capabilities of MRI in diagnosing different tumor dissemination patterns.


disseminated ovarian cancer
peritoneal canceromatosis
magnetic-resonance imaging (MRI)


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Received 06.07.2020

Accepted 27.07.2020

About the Authors

Egor M. Syrkashev, MD, Researcher of the Radiology Department, National Medical Research Center for Obstetrics, Gynecology and Perinatology
named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation. E-mail: 4 Oparin str., 117997, Moscow, Russia.
Alina E. Solopova, PhD in Medical sciences, Leading Researcher, Radiology Department, National Medical Research Center for Obstetrics, Gynecology and Perinatology
named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation. E-mail: 4 Oparin str., 117997, Moscow, Russia
Elena G. Kulabukhova, MD, PhD, Radiology Department, National Medical Research Center for Obstetrics, Gynecology and Perinatology
named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation. 4 Oparin str., 117997, Moscow, Russia

For citation: Syrkashev E.M., Solopova A.E., Kulabukhova E.A.Magnetic resonance imaging in the diagnosis of peritoneal carcinomatosis indisseminated ovarian cancer.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2020; 9: 38-47 (in Russian).
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