The classical and new aspects of human papillomavirus infection: Its impact on reproductive function
Objective. To analyze current literature data on the role of papillomavirus infection in impairing female and male fertility and the impact of the infection on the effectiveness of in vitro fertilization programs.Bashmakova N.V., Osipenko A.A., Lisovskaya T.V., Makutina V.A.
Subjects and methods. The literature sources published in NSBI, PubMed, Medline, and other databases with a search depth of up to 10 years were sought. A total of 135 sources on this topic were analyzed; 41 of them were included in this review.
Results. Some cases of unspecified (idiopathic) infertility are attributable to the presence of human papillomavirus in both women and men. Human papillomavirus may be one of the reasons for failures of assisted reproductive technologies.
Conclusion. There is a need for further investigations of the impact of human papillomavirus on the outcomes of assisted reproductive technology programs and for determination of management tactics for these patients.
Keywords
human papillomavirus
infertility
in vitro fertilization
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Received 13.01.2017
Accepted 17.02.2017
About the Authors
Bashmakova Nadezhda Vasilyevna, MD., professor, director of the Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia. 620028, Russia, Ekaterinburg, Repina str. 1. Tel.: +73433718768. E-mail:dr@niiomm.ruOsipenko Anna Anatolyevna, the postgraduate student of the Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia; gynecologist of the Center for Family Medicine. 620043, Russia, Ekaterinburg, Nachdiva Vasilyeva str. 1/3. Tel.: +73432371999. E-mail: osipenko@cfm.ru
Lisovskaya Tatyana Valentinovna, MD., deputy director on science of the Center for Family Medicine; leading researcher of reproductive health preservation department, Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia. 620028, Russia, Ekaterinburg, Repina str. 1. Tel.: +73433718768. E-mail: tv.lis@mail.ru
Makutina Valerya Andreevna, PhD, embryologist of the Center for Family Medicine. 620043, Russia, Ekaterinburg, Nachdiva Vasil’eva str. 1/3. Tel.: +73432371999.
Е-mail: makutina_v@rambler.ru
For citations: Bashmakova N.V., Osipenko A.A., Lisovskaya T.V., Makutina V.A. The classical and new aspects of human papillomavirus infection: Its impact on reproductive function. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (9): 28-33. (in Russian)
http://dx.doi.org/10.18565/aig.2017.9.28-33
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