CLINICAL PRESENTATION, DIAGNOSTIS AND TREATMENT OF DISEASES ASSOCIATED WITH PAPILLOMAVIRUS INFECTION. GENITAL WARTS

Prilepskaya V.N., Abakarova P.R., Dovletkhanova E.R.

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Ministry of Healthcare of the Russian Federation, Moscow, Russia

Papillomavirus infection (PVI) is one of the most common infections in the modern world. It is known that the human papillomavirus (HPV) is the main cause of diseases of the cervix, vagina, vulva, anus and cervical cancer, genital warts [1].

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Anogenital (venereal) warts are a viral disease caused by HPV and characterized by the appearance of exophytic growths on the skin and mucous membranes of the external genitals, urethra, vagina, cervix, and perianal region [3]. This is the most common clinical form of PVI. According to the Ministry of Health of the Russian Federation, the incidence rate in 2018 was 18.8 per 100 thousand population, and it was 14.9 per 100 thousand population in Moscow [4].

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References

1. Zur Hausen H. Papillomaviruses in the causation of human cancers a brief historical account. // Virology. 2009. Vol. 384, N 2. P. 260–265.

2. E.R. Dovletkhanova, V.N. Prilepskaya. Papillomavirus infection. Theoretical and practical aspects. GEOTAR-Media. 2018. 88 p.

3. Centers for Disease Control and Prevention, Sexually Transmitted Diseases Treatment Guidelines, 2015.

4. Incidence of sexually transmitted infections, infectious skin diseases and skin diseases in 2017-2018 (Statistical materials). Federal state budgetary institution "Central research Institute of health organization and Informatization" of the Ministry of health of the Russian Federation, 2019

5. G.T. Sukhykh, V.N. Prilepskaya, L.A. Ashrafyan, N.M. Nazarova, E.A. Mezhevitinova, S.V. Pavlovich, I.A. Apolikhina, D.Yu.Trofimov, A.E. Donnikov, O.V. Burmenskaya,A.V. Asaturova, M.V. Yurova. Diagnosis, treatment and prevention of HPV-associated cervical diseases in obstetric and gynecological practice. Textbook. M.: LLC "Publishing house "Binom", 2019. 84 p.

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7. Order of the Ministry of health of the Russian Federation dated November 1, 2012 No. 572n "On approval of the Procedure for providing medical care in the field of "obstetrics and gynecology" (except for the use of assisted reproductive technologies).

8. E.R. Dovletkhanova, P.R. Abakarova. Modern possibilities of diagnostics and treatment of HPV-associated diseases of the genitals. medical Council. №3.2020. 107–113.

9. Vaccine against human papillomavirus: the document at the position WHO may 2017. http://www.who.int/immunization/position_papers/position_paper_ process. pdf.

10. instructions for use of the drug for medical use Immunomax. P N001919 / 02-171011.

11. Perlamutrov Yu. N., Soloviev A.M., Ataullakhanov P. P., et al. The use of an activator of antiviral immunity in the complex therapy of recurrent genital warts. Immunopathology, Allergology, Infectology, 2003, No. 3, pp. 138-141.

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