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The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
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Obstetrics and Gynegology2023№8
Echinococcosis of the lung and...

Echinococcosis of the lung and pregnancy

DOI
https://dx.doi.org/10.18565/aig.2023.98

Ignatko I.V., Bogomazova I.M., Timokhina E.V., Belousova V.S., Muravina E.L., Samoylova Yu.A., Rasskazova T.V., Zayratyants G.O., Salakhutdinova A.N.

1) I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia; 2) S.S. Yudin City Clinical Hospital, Moscow City Healthcare Department, Moscow, Russia; 3) A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation, Moscow, Russia
Background: Echinococcosis is a parasitic disease caused by the larvae of tapeworms. In the gastrointestinal tract of intermediate hosts, which are herbivores and humans, oncospheres are released, hematogenically spreading through the systemic circulation and most frequently affecting the liver (44–85%) and lung (15–20%). The clinical symptoms of human echinococcosis depend on the site and size of cysts. Instrumental diagnosis is based on the use of various imaging methods. A decrease in cellular immunity and a rise in the concentration of steroid hormones during pregnancy lead to a significant increase in echinococcal cysts, which is often complicated by their rupture.
Case report: A 36-year-old repeatedly pregnant woman at 30 weeks’ gestation was taken to an obstetric hospital with complaints of paroxysmal cough and a feeling of lack of air with an oxygen saturation level of 94%. When examining the patient, the physicians found tachypnea, tachycardia, and progressive dyspnea. Blood tests detected hypoxemia, hypocapnia, and elevated C-reactive protein levels. Chest computed tomography revealed rounded masses in the lower lobes of the both lungs with a layered capsule and subcapsular arrangement of gas bubbles corresponding to the presence of parasitic cysts. A decision was made to surgically remove the masses with a preliminary early delivery of the patient. The histological examination data confirmed the echinococcal genesis of lung damage.
Conclusion: In the third trimester of pregnancy, rapid uterine growth rates associated with higher intraabdominal pressure and with the upward displacement of the diaphragm are a high risk factor for parasitic cyst rupture, which poses a threat to the life of the mother and her fetus due to the development of an anaphylactic reaction. Since surgical removal of cysts on during prolonged pregnancy also creates a risk of their rupture; at the first stage, the patient was prematurely delivered via cesarean section. Owing to the coordinated interaction of specialists of various profiles, the maternal and perinatal outcomes turned out to be favorable.

Authors' contributions: Ignatko I.V., Muravina E.L., Bogomazova I.M. – concept and design of the study; Bogomazova I.M., Salakhutdinova A.N., Zayratyants G.O. – collection and processing of the material; Bogomazova I.M., Samoylova Yu.A., Rasskazova T.V. – data processing; Bogomazova I.M., Salakhutdinova A.N. – writing a text; Ignatko I.V., Timokhina E.V., Belousova V.S. – editing.
Conflicts of interest: The authors declare lack of the possible conflicts of interests.
Funding: The authors declare lack of the funding.
Patient Consent for Publication: The patient provided informed consent for the publication of her data and associated images.
For citation: Ignatko I.V., Bogomazova I.M., Timokhina E.V., Belousova V.S., Muravina E.L., Samoylova Yu.A., Rasskazova T.V., Zayratyants G.O., Salakhutdinova A.N.
Echinococcosis of the lung and pregnancy.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2023; (8): 216-222 (in Russian)
https://dx.doi.org/10.18565/aig.2023.98

Keywords

echinococcosis and pregnancy
echinococcosis of the lung
echinococcal cyst of the lung
Full text (in Russian)

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Received 13.04.2023

Accepted 03.05.2023

About the Authors

Irina V. Ignatko, Dr. Med. Sci., Corresponding Member of the Russian Academy of Sciences, Professor of the Russian Academy of Sciences, Professor, Head of the Department of Obstetrics, Gynecology and Perinatology, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), +7(499)782-30-45, ignatko_i_v@staff.sechenov.ru, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Irina M. Bogomazova, PhD, Associate Professor of the Department of Obstetrics, Gynecology and Perinatology, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), +7(926)305-04-03, bogomazova_i_m@staff.sechenov.ru,
https://orcid.org/0000-0003-1156-7726, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Elena V. Timokhina, Dr. Med. Sci., Associate Professor, Professor of the Department of Obstetrics, Gynecology and Perinatology, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), +7(499)782-30-45,
timokhina_i_m@staff.sechenov.ru, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Vera S. Belousova, Dr. Med. Sci., Associate Professor, Professor of the Department of Obstetrics, Gynecology and Perinatology, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), +7(499)782-30-45, belousova_v_s@staff.sechenov.ru, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Elena L. Muravina, PhD, Deputy Chief Physician for Obstetrics and Gynecology, S.S. Yudin City Clinical Hospital of the Moscow City Health Department, +7(499)782-30-64, gkb-yudina@zdrav.mos.ru, 115446, Russia, Moscow, Kolomensky proezd, 4.
Yulia A. Samoylova, PhD, Head of the Department of Pregnancy Pathology №1 of the Maternity Hospital, S.S. Yudin City Clinical Hospital of the Moscow City Health Department, +7(499)782-30-64, gkb-yudina@zdrav.mos.ru, 115446, Russia, Moscow, Kolomensky proezd, 4.
Tatyana V. Rasskazova, obstetrician-gynecologist of the Department of pregnancy Pathology №1 of the Maternity Hospital, S.S. Yudin City Clinical Hospital of the Moscow City Health Department, +7(499)782-30-64, gkb-yudina@zdrav.mos.ru, 115446, Russia, Moscow, Kolomensky proezd, 4.
Georgy O. Zayratyants, PhD, Head of the Pathology Department, S.S. Yudin City Clinical Hospital of the Moscow City Health Department, +7(499)782-30-64,
gkb-yudina@zdrav.mos.ru, 115446, Russia, Moscow, Kolomensky proezd, 4; Associate Professor of the Department of Pathological Anatomy of the Medical Faculty,
A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation, +7(495)609-67-00, msmsu@msmsu.ru, 127473, Russia, Moscow, Delegatskaya str., 20-1.
Azaliya N. Salakhutdinova, student of the N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), +7(499)782-30-45, calaxutdinova@yandex.ru, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Corresponding author: Irina M. Bogomazova, bogomazova_i_m@staff.sechenov.ru
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